Evaluation of static and dynamic Pupillometry changes in men using Silodosin for benign prostatic hypertrophy

Abstract Background Intraoperative floppy iris syndrome is a variant of the small pupil that has been observed during cataract surgery in some patients currently or previously treated with α1 adrenergic blockers. It important for surgeons to predict probable complications preoperatively. Our study aims evaluate static and dynamic characteristics silodosin—a selective blocker—for benign prostate hypertrophy (BPH) compare these values healthy subjects using an automatic quantitative pupillometry system. Methods A total 74 BPH silodosin six months (group 1) 30 2) were enrolled this prospective multidisciplinary cross-sectional study. Static pupillometric measurements obtained under optimized conditions, results compared between two groups. Results Seventy-four male mean age 63,35 ± 7,21 (46–77) years normal 63,07 4,73 (52–71) analyzed. There statistically significant differences groups regard scotopic diameter (PD), high photopic PD, low PD ( p < 0.001, each one). The patient group had higher amplitude velocity contraction lower duration latency as well dilation. Conclusion are different from those eyes. In addition, our may have shed light on risk intraoperative (IFIS) before surgery; thus, can be alert take precautions.